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Guayaquil Known as the ‘Pacific Pearl’, the history of Guayaquil has always been intimately tied to the Rio Guayas. As the economic powerhouse of Ecuador, Guayaquil is a city in transition, transforming itself into a modern metropolis while managing to retain its cultural heritage. Stroll along the Malecon 2000, one of South America’s largest reconstruction projects, running along the Guayas River and discover green public spaces, blue ponds, shopping, restaurants, river boat excursions and a handicraft market. Guayaquil is the gateway for excursions to the natural wonders of the Galapagos Islands, one of the world’s most important wildlife areas.